SCHEMBL4103807

SCHEMBL4103807

COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(OC(C)(C)C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.58
PPARG P37231 10/20 0.58
MAPT P10636 5/20 0.57
TP53 P04637 2/20 0.52
FFAR1 O14842 1/20 0.52
POLB P06746 1/20 0.51
PPARD Q03181 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4107292 0.92 PPARA (0.69) PPARAPPARGPPARD
SCHEMBL4755678 0.91 MAPT (0.57) PPARAPPARGMAPTTP53FFAR1
SCHEMBL4097135 0.89 MAPT (0.49) PPARAPPARGMAPTTP53POLB
SCHEMBL4099013 0.89 MAPT (0.47) PPARAPPARGMAPTTP53POLB
SCHEMBL4092427 0.88 MAPT (0.61) PPARAPPARGMAPTTP53FFAR1
SCHEMBL4109852 0.88 MAPT (0.61) PPARAPPARGMAPTTP53FFAR1
SCHEMBL4102445 0.87 PPARA (0.49) PPARAPPARGMAPTPOLBPPARD
SCHEMBL4100506 0.86 FFAR1 (0.60) PPARAPPARGMAPTTP53FFAR1
SCHEMBL4098230 0.86 MAPT (0.62) PPARAPPARGMAPTTP53FFAR1
SCHEMBL4756249 0.85 MAPT (0.61) PPARAPPARGMAPTTP53FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US claimed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP claimed
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC PPARA 8/4885PPARG 23/4885MAPT 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.