SCHEMBL409920

SCHEMBL409920

O=P(Cl)(Cl)N1CCOCC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
GAA P10253 2/20 0.42
MMP1 P03956 1/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
ALPG P10696 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CA12 O43570 2/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MGLL Q99685 1/20 0.33
ANPEP P15144 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28287137 0.97 MAPT (0.42) MAPTGAAMMP1MMP3MMP8
SCHEMBL2844045 0.83 MAPT (0.43) MAPTGAAMMP1MMP3MMP8
SCHEMBL28237924 0.79 MAPT (0.41) MAPTGAAMMP1MMP3MMP8
SCHEMBL7455288 0.79 MMP1 (0.46) MAPTGAAMMP1MMP3MMP8
SCHEMBL9518240 0.79 GAA (0.41) MAPTGAAMMP1MMP3MMP8
SCHEMBL1276983 0.77 MAPT (0.46) MAPTGAAMMP1MMP3MMP8
SCHEMBL29727668 0.74 MAPT (0.45) MAPTGAAMMP1MMP3MMP8
SCHEMBL11531391 0.74 MAPT (0.45) MAPTGAAMMP1MMP3MMP8
SCHEMBL38651931 0.73
SCHEMBL329843 0.72 MMP1 (0.50) MAPTGAAMMP1MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080571-A Weather-resistant polyoxymethylene automobile sun visor material and preparation method thereof 2026-05-26 CN claimed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
WO-2024137495-A1 FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF NAVINTA, LLC (US) 2024-06-27 WO claimed
CN-114643075-B Catalyst for synthesizing alkylene carbonate, and preparation method and application thereof 中国石油化工股份有限公司 2023-08-29 CN claimed
CN-113999270-B Method for synthesizing cytidine diphosphate 新乡拓新药业股份有限公司 2023-03-14 CN claimed
CN-113999270-A Method for synthesizing cytidine diphosphate 新乡拓新药业股份有限公司 2022-02-01 CN claimed
CN-105732752-A Citicoline and synthetic method thereof 新乡学院 2016-07-06 CN claimed
CN-105693798-A Citicoline and synthesizing method of citicoline not using phosphocholine chloride calcium 新乡学院 2016-06-22 CN claimed
CN-122103207-A Chiral morpholino phosphoryl chloride monomer and preparation method and application thereof 2026-05-29 CN disclosed
CN-122103207-A Chiral morpholino phosphoryl chloride monomer and preparation method and application thereof 2026-05-29 CN disclosed
CN-122080571-A Weather-resistant polyoxymethylene automobile sun visor material and preparation method thereof 2026-05-26 CN disclosed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
CN-118581179-A Method for synthesizing citicoline sodium by catalyzing cytidine in one pot by multi-enzyme system 深圳华酶生物科技有限公司 2024-09-03 CN disclosed
CN-114643075-B Catalyst for synthesizing alkylene carbonate, and preparation method and application thereof 中国石油化工股份有限公司 2023-08-29 CN disclosed
US-8779128-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2014-07-15 US disclosed
US-8779128-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2014-07-15 US disclosed
US-20120289457-A1 PEPTIDE OLIGONUCLEOTIDE CONJUGATES AVI BIOPHARMA, INC. (US) 2012-11-15 US disclosed
US-20120289457-A1 PEPTIDE OLIGONUCLEOTIDE CONJUGATES AVI BIOPHARMA, INC. (US) 2012-11-15 US disclosed
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2012-03-15 US disclosed
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS NSUN2, UPF1, RTCB MAPT 2188/4885GAA 2322/4885MMP1 4445/4885
US-20120289457-A1 PEPTIDE OLIGONUCLEOTIDE CONJUGATES SNRPE, SMN1; SMN2, UPF1 MAPT 2633/4885GAA 77/4885MMP1 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.