Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409920 | 0.83 | MAPT (0.43) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL28287137 | 0.81 | MAPT (0.42) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL28237924 | 0.79 | MAPT (0.41) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL7455288 | 0.79 | MMP1 (0.46) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL9518240 | 0.79 | GAA (0.41) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL31220775 | 0.78 | — | — | |
| SCHEMBL1276983 | 0.77 | MAPT (0.46) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL11531391 | 0.74 | MAPT (0.45) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL29727668 | 0.74 | MAPT (0.45) | MAPTGAAMMP1MMP3MMP8 | |
| SCHEMBL273145 | 0.72 | MAPT (0.43) | MAPTGAAMMP1MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695257-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SALTS THEREOF | Harman Finochem Limited (IN) | 2026-02-18 | — | — | EP | claimed |
| WO-2024214109-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SALTS THEREOF | HARMAN FINOCHEM LIMITED (IN) | 2024-10-17 | — | — | WO | claimed |
| WO-2024137495-A9 | FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | NAVINTA, LLC (US) | 2024-07-25 | — | — | WO | claimed |
| WO-2024137495-A1 | FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | NAVINTA, LLC (US) | 2024-06-27 | — | — | WO | claimed |
| US-20240208980-A1 | Fostemsavir Intermediates and Process for the Preparation Thereof | NAVINTA, LLC | 2024-06-27 | — | — | US | claimed |
| CN-117761193-A | Analysis and detection method for rimazolam intermediate | 上海药坦药物研究开发有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117486930-A | Phosphonamide flame-retardant nucleation difunctional additive for polyester and preparation method thereof | 江苏康辉新材料科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117229614-A | Flame-retardant heat-resistant polylactic acid composition and preparation method thereof | 江苏康辉新材料科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-112321594-B | Preparation method of benzodiazepine medicine | 扬子江药业集团有限公司 | 2022-05-20 | — | — | CN | claimed |
| US-11236064-B2 | Method for preparing 3-[(3S)-7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-[1,4]-benzodiazepin-3-yl] propionic acid methyl ester, and compounds useful in that method | MOEHS IBERICA S.L. (ES) | 2022-02-01 | — | — | US | claimed |
| EP-3658545-B1 | METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL]PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD | MOEHS IBERICA SL (ES) | 2021-08-11 | — | — | EP | claimed |
| US-20210139452-A1 | METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL] PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD | MOEHS IBERICA S.L. (ES) | 2021-05-13 | — | — | US | claimed |
| CN-112321594-A | Preparation method of benzodiazepine medicine | 扬子江药业集团有限公司 | 2021-02-05 | — | — | CN | claimed |
| EP-3658545-A1 | METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL]PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD | Moehs Ibérica, S.L. (ES) | 2020-06-03 | — | — | EP | claimed |
| WO-2019020790-A1 | METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL] PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD | MOEHS IBERICA S.L. (ES) | 2019-01-31 | — | — | WO | claimed |
| US-20260137765-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2026-05-21 | — | — | US | disclosed |
| EP-4711368-A1 | AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2026-03-18 | — | — | EP | disclosed |
| US-4307237-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4280957-A | Imidazodiazepines and processes therefor | HOFFMANN-LA ROCHE INC. (US) | 1981-07-28 | — | — | US | disclosed |
| US-3974188-A | PHOSPHATE | THE LION DENTIFRICE CO., LTD. (JA) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139452-A1 | METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL] PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD | GABRA3, GRIK5, GABRA6 | MAPT 2663/4885GAA 4104/4885MMP1 4780/4885 |
| US-11236064-B2 | Method for preparing 3-[(3S)-7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-[1,4]-benzodiazepin-3-yl] propionic acid methyl ester, and compounds useful in that method | GABRA3, GRIK5, GABRA6 | MAPT 2663/4885GAA 4104/4885MMP1 4780/4885 |
| US-20240208980-A1 | Fostemsavir Intermediates and Process for the Preparation Thereof | FIP1L1, CYP3A4, FOS | MAPT 1017/4885GAA 511/4885MMP1 4233/4885 |
| US-20260137765-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | STXBP1, HBB, UPF1 | MAPT 3405/4885GAA 3170/4885MMP1 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.