Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094266 | 0.78 | RAB9A (0.47) | POLBKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2986833 | 0.73 | HDAC1 (0.39) | POLBKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4094548 | 0.70 | KDM4E (0.42) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2019847 | 0.69 | EPHX2 (0.43) | KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL1492740 | 0.69 | DAO (0.43) | POLBKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2654268 | 0.68 | ALDH1A1 (0.41) | POLBSMN1; SMN2RAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9402263 | 0.68 | DAO (0.42) | POLBKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9235584 | 0.68 | CNR1 (0.40) | POLBKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5758336 | 0.68 | MAPT (0.48) | POLBKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6675248 | 0.66 | DAO (0.41) | KMT2ASMN1; SMN2ALDH1A1GAACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1995243-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | HSD11B1, HSD11B2, HSD17B1 | POLB 2629/4885KMT2A 1938/4885SMN1; SMN2 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.