Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 9/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485216 | 0.82 | DRD2 (0.56) | TBXA2RDRD2DRD3 | |
| SCHEMBL1682787 | 0.82 | DRD2 (0.56) | TBXA2RDRD2DRD3 | |
| SCHEMBL11355027 | 0.74 | BCL2L1 (0.48) | TBXA2R | |
| SCHEMBL9070606 | 0.74 | BCL2L1 (0.44) | TBXA2R | |
| SCHEMBL529887 | 0.69 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL15051975 | 0.69 | TBXA2R (0.62) | TBXA2RDRD2HTR1ADRD1HTR7 | |
| SCHEMBL32685224 | 0.67 | BCL2L1 (0.36) | TBXA2RDRD2 | |
| SCHEMBL7554445 | 0.66 | DRD2 (0.63) | DRD2DRD3 | |
| SCHEMBL8993281 | 0.66 | PNMT (0.60) | DRD2DRD3DRD4HTR7 | |
| SCHEMBL22319819 | 0.65 | S1PR5 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063171-A1 | NOVEL ROTIGOTINE SALTS | PLIVA HRVATSKA D.O.O. (HR) | 2009-05-22 | — | — | WO | disclosed |