Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 1.00 |
| ▸ | CA1 | P00915 | 2/20 | 1.00 |
| ▸ | CA2 | P00918 | 2/20 | 1.00 |
| ▸ | CA9 | Q16790 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | NOS3 | P29474 | 1/20 | 0.65 |
| ▸ | NOS2 | P35228 | 1/20 | 0.65 |
| ▸ | SLC22A2 | O15244 | 6/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 6/20 | 0.61 |
| ▸ | SLC22A3 | O75751 | 6/20 | 0.61 |
| ▸ | PLAU | P00749 | 5/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.61 |
| ▸ | HTR3B | O95264 | 4/20 | 0.61 |
| ▸ | HTR3A | P46098 | 4/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3126857 | 0.97 | CA12 (1.00) | CA12CA1CA2CA9POLB | |
| Nitric Acid SCHEMBL6033862 | 0.85 | CA12 (0.72) | CA12CA1CA2CA9POLB | |
| SCHEMBL1738380 | 0.80 | POLB (0.82) | CA12CA1CA2CA9POLB | |
| SCHEMBL5605757 | 0.78 | POLB (0.78) | CA12CA1CA2CA9POLB | |
| Iodide SCHEMBL3529244 | 0.77 | CA12 (0.62) | CA12CA1CA2CA9POLB | |
| SCHEMBL2447318 | 0.76 | SLC22A2 (1.00) | CA12CA1CA2CA9POLB | |
| SCHEMBL4100900 | 0.76 | HTR3E (1.00) | CA12CA1CA2CA9POLB | |
| Hydrochloric Acid SCHEMBL7249756 | 0.76 | POLB (0.74) | CA12CA1CA2CA9POLB | |
| SCHEMBL7624064 | 0.76 | SLC22A2 (1.00) | CA12CA1CA2CA9POLB | |
| SCHEMBL166140 | 0.76 | SLC22A2 (1.00) | CA12CA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| CN-1860104-A | 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors | CYCLACEL LTD (GB) | 2006-11-08 | — | — | CN | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | CA12 2835/4885CA1 3081/4885CA2 1106/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | CA12 3511/4885CA1 3572/4885CA2 3522/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | CA12 3323/4885CA1 3665/4885CA2 3761/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | CA12 2752/4885CA1 2285/4885CA2 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.