SCHEMBL166140

SCHEMBL166140

Cc1ccc(N=C(N)N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 7/20 1.00
SLC22A1 O15245 7/20 1.00
SLC22A3 O75751 7/20 1.00
PLAU P00749 6/20 1.00
HTR3E A5X5Y0 5/20 1.00
HTR3B O95264 5/20 1.00
HTR3A P46098 5/20 1.00
HTR3D Q70Z44 5/20 1.00
HTR3C Q8WXA8 5/20 1.00
POLB P06746 1/20 0.74
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA9 Q16790 2/20 0.61
PRSS1 P07477 1/20 0.59
ACR P10323 1/20 0.59
CYP2D6 P10635 1/20 0.58
CYP2C19 P33261 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ADRA2A P08913 5/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038561 0.81 HTR3E (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL1738380 0.78 POLB (0.82) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL27504473 0.77 GRIN2D (0.66) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL1520845 0.77 SIGMAR1 (0.66) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL4099993 0.76 CA12 (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL27552961 0.76 HTR3E (0.61) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL14816923 0.76 HTR3E (0.61) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL5605757 0.76 POLB (0.78) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Methylamine SCHEMBL11079804 0.75 SLC22A2 (0.91) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Iodide SCHEMBL10827683 0.75 NOS3 (0.69) SLC22A2SLC22A1SLC22A3PLAUHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735905-A Metal rubber composite material applied to liquid hydrogen sealing and preparation process 成都天府垫片科技有限公司 2025-04-01 CN claimed
CN-107698916-B Wide temperature range acrylic rubber base graphene oxide damping material and preparation method thereof 南京理工大学 2019-11-15 CN claimed
CN-108034177-A Wide temperature range acrylic rubber base nano silicon dioxide damping material and preparation method thereof 南京理工大学 2018-05-15 CN claimed
CN-107828167-A ACM base cellulose whiskers damping materials and preparation method thereof 南京理工大学 2018-03-23 CN claimed
CN-107698916-A Wide temperature range ACM base graphene oxide damping material and preparation method thereof 南京理工大学 2018-02-16 CN claimed
EP-1449881-B1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KK (JP) 2014-06-18 EP claimed
WO-2014012979-A2 LATEX COMPOSITION SOBELTEC (BE) 2014-01-23 WO claimed
US-20100018600-A1 HIGH TEMPERATURE-RESISTANT HOSE FLUID ROUTING SOLUTIONS, INC. 2010-01-28 US claimed
JP-2009514771-A 2009-04-09 JP claimed
EP-1991431-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.p.A. (IT) 2008-11-19 EP claimed
EP-1945710-A2 NANOCOMPOSITE COMPOSITIONS AND PROCESSES FOR MAKING THE SAME ExxonMobil Chemical Patents Inc. (US) 2008-07-23 EP claimed
WO-2007098784-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2007-09-07 WO claimed
WO-2007055793-A2 NANOCOMPOSITE COMPOSITIONS AND PROCESSES FOR MAKING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-18 WO claimed
EP-1449881-A1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-08-25 EP claimed
EP-1161487-A4 LIQUID EBONITE MIXTURES AND COATINGS AND CONCRETES FORMED THEREFROM EUROTECH LTD (US) 2003-05-02 EP claimed
EP-1161487-A1 LIQUID EBONITE MIXTURES AND COATINGS AND CONCRETES FORMED THEREFROM Eurotech, Ltd. (US) 2001-12-12 EP claimed
WO-2000006639-A1 LIQUID EBONITE MIXTURES AND COATINGS AND CONCRETES FORMED THEREFROM EUROTECH LTD. (US) 2000-02-10 WO claimed
EP-0171154-B1 CURED RUBBER BLEND AND PROCESS FOR THE PRODUCTION THEREOF UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-09-06 EP claimed
JP-5051477-A None JP disclosed
JP-S5452013-A ISOMERIZATION OF DICHLOROBUTENE DENKI KAGAKU KOGYO KK 1979-04-24 JP disclosed