Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28418398 | 0.87 | ERN1 (0.57) | ERN1LMNABACE1ALDH1A1MAPT | |
| SCHEMBL12587469 | 0.84 | ERN1 (0.46) | ERN1LMNABACE1ALDH1A1MAPT | |
| SCHEMBL12587575 | 0.84 | GAA (0.38) | ERN1LMNABACE1ALDH1A1ROR1 | |
| SCHEMBL4000526 | 0.83 | ERN1 (0.38) | ERN1LMNABACE1ALDH1A1MAPT | |
| SCHEMBL12586745 | 0.83 | HTR1D (0.33) | ERN1BACE1HDAC8 | |
| SCHEMBL4099200 | 0.83 | ERN1 (0.65) | ERN1LMNAALDH1A1NQO2CYP19A1 | |
| SCHEMBL12587154 | 0.82 | PDIA6 (0.34) | ERN1HDAC8 | |
| SCHEMBL30401888 | 0.81 | ERN1 (0.41) | ERN1LMNABACE1ALDH1A1ROR1 | |
| SCHEMBL2028419 | 0.81 | BACE1 (0.42) | ERN1BACE1MAPTCYP3A4 | |
| SCHEMBL12586411 | 0.80 | ERN1 (0.43) | ERN1LMNABACE1ALDH1A1ROR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329742-B2 | Macrocyclic compounds useful as pharmaceuticals | EISAI CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20110144101-A1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | EISAI CO., LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| US-20090054435-A1 | Phenoxyalkanoic Acid Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1911738-A1 | PHENOXYALKANOIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144101-A1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | FLT1, TBXA2R, VEGFA | ERN1 3392/4885LMNA 3424/4885BACE1 3092/4885 |
| US-20090054435-A1 | Phenoxyalkanoic Acid Compound | PNLIP, GPR119, LIPC | ERN1 3836/4885LMNA 2967/4885BACE1 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.