SCHEMBL557449

SCHEMBL557449

CC(=O)Oc1ccc2cc(C(=O)c3cc4ccc(OC(C)=O)cc4oc3=O)c(=O)oc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.65
ALDH1A1 P00352 7/20 0.65
GLA P06280 6/20 0.65
GAA P10253 6/20 0.65
HPGD P15428 4/20 0.65
HSD17B10 Q99714 2/20 0.65
CASP1 P29466 1/20 0.65
CASP7 P55210 1/20 0.65
CA12 O43570 4/20 0.64
CA9 Q16790 4/20 0.64
POLB P06746 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
RAB9A P51151 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
NPC1 O15118 2/20 0.64
MAOB P27338 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.60
SLC16A3 O15427 1/20 0.59
PKM P14618 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378625 1.00 KDM4E (0.65) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL5940913 0.91 GAA (0.76) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL6836395 0.91 ALDH1A1 (0.79) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL4101829 0.90 SLC16A3 (0.74) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL2336577 0.89 KDM4E (0.62) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL5940918 0.85 KDM4E (0.58) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL52650 0.85 ALDH1A1 (0.81) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL2394277 0.84 MAOB (0.77) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL4769996 0.84 KDM4E (0.67) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL7884546 0.82 KDM4E (0.65) KDM4EALDH1A1GLAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4736835-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-12371521-B2 Photosensitive composition, hologram recording medium using the same, hologram optical element, and method of forming hologram diffraction grating Sony Group Corporation (JP) 2025-07-29 US disclosed
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-5698345-A CATIONIC POLYMERIZATION OF THERMOSETTING EPOXY OLIGOMER TOPPAN PRINTING CO., LTD. (JP) 1997-12-16 US disclosed
EP-0697631-A1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1996-02-21 EP disclosed
EP-0672953-A2 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1995-09-20 EP disclosed
EP-0276016-B1 PHOTOPOLYMERIZABLE COMPOSITION Nippon Paint Co., Ltd. (JP) 1992-08-12 EP disclosed
US-4965171-A POLYMERIZABLE, ETHYLENICALLY UNSATURATED COMPONENT WITH PHOTOINITIATOR OF COUMARIN DYE, DIARYLIODONIUM SALT AND AMINE OR THIOPHENOXYACETIC ACID NIPPON PAINT CO., LTD. (JP) 1990-10-23 US disclosed
US-4948694-A CONTAINING PHOTOINITIATOR COMPRISING CAMPHORQUINONE AND COUMARIN DERIVATIVE; SENSITIVITY, STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1990-08-14 US disclosed
US-4868092-A SENSITIVE TO VISIBLE LIGHT, XANTHENE DYE INITIATOR NIPPON PAINT CO., LTD. (JP) 1989-09-19 US disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE CDH1, MACF1, ICAM1 KDM4E 3559/4885ALDH1A1 695/4885GLA 2146/4885
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 KDM4E 2952/4885ALDH1A1 1885/4885GLA 3801/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A KDM4E 1086/4885ALDH1A1 1780/4885GLA 84/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A KDM4E 2118/4885ALDH1A1 306/4885GLA 2473/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL KDM4E 2312/4885ALDH1A1 668/4885GLA 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.