SCHEMBL4102376

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4093018	0.86	KDM4E (0.58)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL9541072	0.82	KDM4E (0.50)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL27407297	0.80	KDM4E (0.51)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL7539997	0.79	KDM4E (0.50)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL2896096	0.79	KDM4E (0.52)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL259035	0.77	ALDH1A1 (0.54)	KDM4EALDH1A1TP53IKBKBCHUK
	SCHEMBL27419975	0.74	KDM4E (0.48)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL4849845	0.73	KDM4E (0.62)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL11339514	0.71	KDM4E (0.44)	KDM4EALDH1A1GAATHRBTP53
	SCHEMBL843920	0.71	KDM4E (0.56)	KDM4EALDH1A1THRBTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.