Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 4/20 | 0.31 |
| ▸ | PPARD | Q03181 | 4/20 | 0.31 |
| ▸ | PPARA | Q07869 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20390493 | 0.98 | PAOX (0.40) | PAOXGAAALDH1A1TDP1ACHE | |
| SCHEMBL11118300 | 0.92 | ALDH1A1 (0.38) | PAOXALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL4528611 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4522923 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4528271 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4517033 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4528299 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL1054786 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4532402 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA | |
| SCHEMBL4531810 | 0.84 | GPR84 (0.50) | ALDH1A1TDP1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062234-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD. (GB) | 2009-03-05 | — | — | US | disclosed |
| EP-1791891-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | Phosphonics LTD (GB) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006013080-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062234-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | OR10J3, OPRM1, MSR1 | PAOX 1710/4885GAA 2929/4885ALDH1A1 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.