Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27118454 | 1.00 | MEN1 (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL21284233 | 1.00 | MEN1 (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL2367531 | 0.96 | MEN1 (0.55) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7364210 | 0.96 | MEN1 (0.55) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL1486276 | 0.96 | MEN1 (0.55) | MEN1GAAKMT2AALDH1A1TSHR | |
| Water SCHEMBL10332189 | 0.95 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7264801 | 0.95 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8630295 | 0.95 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10444447 | 0.95 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1TSHR | |
| Water SCHEMBL10332190 | 0.95 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| WO-1989007609-A1 | HOMOARGININE-BASED PEPTIDES AS PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1989-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | MEN1 3310/4885GAA 873/4885KMT2A 2037/4885 |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | MEN1 3310/4885GAA 873/4885KMT2A 2037/4885 |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | MEN1 261/4885GAA 4688/4885KMT2A 322/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | MEN1 294/4885GAA 3613/4885KMT2A 555/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | MEN1 237/4885GAA 4099/4885KMT2A 949/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | MEN1 455/4885GAA 1616/4885KMT2A 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.