Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468024 | 0.78 | NAMPT (0.36) | NAMPT | |
| SCHEMBL11434822 | 0.78 | NAMPT (0.36) | NAMPT | |
| SCHEMBL11261571 | 0.75 | ALDH1A1 (0.38) | NAMPT | |
| SCHEMBL11634443 | 0.75 | NAMPT (0.35) | NAMPT | |
| SCHEMBL11174808 | 0.74 | NAMPT (0.34) | NAMPT | |
| SCHEMBL6825745 | 0.74 | NAMPT (0.34) | NAMPT | |
| SCHEMBL10242486 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27945144 | 0.71 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL327494 | 0.71 | — | — | |
| SCHEMBL29629110 | 0.70 | ALOX5 (0.61) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038278-A2 | THIAZOLINE AND OXAZOLINE DERIVATIVES AND THEIR METHODS OF USE | Abbott Laboratories (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008002956-A2 | THIAZOLINE AND OXAZOLINE DERIVATIVES AND THEIR METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-01-03 | — | — | WO | disclosed |