Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261571 | 0.79 | ALDH1A1 (0.38) | NAMPTALDH1A1 | |
| SCHEMBL11434822 | 0.78 | NAMPT (0.36) | NAMPT | |
| SCHEMBL4107607 | 0.78 | NAMPT (0.36) | NAMPT | |
| SCHEMBL11174808 | 0.78 | NAMPT (0.34) | NAMPT | |
| SCHEMBL11634443 | 0.75 | NAMPT (0.35) | NAMPT | |
| SCHEMBL9957440 | 0.74 | KDM4E (0.40) | — | |
| SCHEMBL6825745 | 0.74 | NAMPT (0.34) | NAMPT | |
| SCHEMBL9954309 | 0.73 | — | — | |
| SCHEMBL327494 | 0.71 | — | — | |
| SCHEMBL21058086 | 0.70 | ALOX5 (0.45) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291622-B2 | Medical uses of carbamate-substituted pyrazolo-pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7105523-B2 | Carbamate-substituted pyrazolopyridine-derivatives | BAYER AKTIENGESELISCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20050261323-A1 | Medical uses of novel carbamate-substituted pyrazolopyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261323-A1 | Medical uses of novel carbamate-substituted pyrazolopyridine derivatives | NOS3, NOX3, NPR3 | NAMPT 1272/4885ALDH1A1 1891/4885TSHR 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.