Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756749 | 0.85 | TRPV1 (0.43) | LIPEMAPK1KMT2ATSHRRAB9A | |
| SCHEMBL14312475 | 0.83 | HPGDS (0.37) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL4096892 | 0.80 | KMT2A (0.49) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL14312669 | 0.78 | HPGDS (0.45) | KMT2ARAB9AMGLL | |
| SCHEMBL4108478 | 0.78 | CA12 (0.52) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL8836159 | 0.77 | NOTUM (0.42) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL9194011 | 0.77 | ALDH1A1 (0.46) | MAPK1KMT2ATSHRRAB9ACA12 | |
| SCHEMBL10973432 | 0.75 | NOTUM (0.55) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL31414100 | 0.75 | LMNA (0.47) | MAPK1KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL30371592 | 0.75 | NOTUM (0.55) | MAPK1KMT2ATSHRRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | TPH1, HTR1D, IDO1 | LIPE 3528/4885MAPK1 81/4885KMT2A 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.