Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102885 | 0.81 | SLC6A2 (0.49) | L3MBTL1SLC6A2NOTUMALDH1A1KMT2A | |
| SCHEMBL10975857 | 0.78 | NOTUM (0.53) | L3MBTL1TDP1SLC6A2NOTUMKMT2A | |
| SCHEMBL8836092 | 0.73 | SLC6A2 (0.44) | L3MBTL1SLC6A2NOTUMKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL8835946 | 0.72 | SLC6A2 (0.43) | L3MBTL1SLC6A2NOTUMALDH1A1KMT2A | |
| SCHEMBL8118593 | 0.71 | SLC6A2 (0.49) | L3MBTL1SLC6A2NOTUMALDH1A1KMT2A | |
| SCHEMBL30760162 | 0.70 | TSHR (0.57) | L3MBTL1NOTUMALDH1A1PKMKMT2A | |
| Phenyl Dimethylcarbamate SCHEMBL491227 | 0.69 | RAB9A (0.78) | L3MBTL1ATMTDP1ALDH1A1PKM | |
| SCHEMBL7194185 | 0.69 | TDP1 (0.61) | L3MBTL1ATMTDP1ALDH1A1PKM | |
| SCHEMBL11212298 | 0.69 | TDP1 (0.61) | L3MBTL1ATMTDP1ALDH1A1PKM | |
| SCHEMBL3365470 | 0.69 | SLC6A2 (0.58) | SLC6A2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2009-07-09 | — | — | US | disclosed |
| CN-101475560-A | New 1H-indol-1-yl-urea compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2009-07-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | TPH1, HTR1D, IDO1 | L3MBTL1 288/4885ATM 3589/4885TDP1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.