Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8835946 | 0.98 | SLC6A2 (0.43) | SLC6A2NOTUMLMNAKMT2AHTR2A | |
| SCHEMBL10975857 | 0.80 | NOTUM (0.53) | SLC6A2NOTUMLMNAKMT2AHTR2A | |
| SCHEMBL4102885 | 0.80 | SLC6A2 (0.49) | SLC6A2NOTUMLMNAKMT2AHTR2A | |
| SCHEMBL8836095 | 0.75 | LMNA (0.49) | SLC6A2NOTUMLMNAKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL8835948 | 0.74 | LMNA (0.48) | SLC6A2NOTUMLMNAKMT2AHTR2A | |
| SCHEMBL8118593 | 0.73 | SLC6A2 (0.49) | SLC6A2NOTUMKMT2AHTR2AHTR2C | |
| SCHEMBL4108676 | 0.73 | L3MBTL1 (0.42) | SLC6A2NOTUMKMT2AMAPK1TSHR | |
| SCHEMBL3365470 | 0.72 | SLC6A2 (0.58) | SLC6A2NOTUMHTR2AHTR2CCDK4 | |
| SCHEMBL10733096 | 0.70 | SLC6A2 (0.46) | SLC6A2NOTUMLMNAKMT2AMAPK1 | |
| SCHEMBL25937249 | 0.69 | NOTUM (0.61) | NOTUMLMNAKMT2AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319096-A | Neuroprotective agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-06-07 | — | — | US | claimed |
| US-5646300-A | NEUROPROTECTIVE AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5591866-A | NEUROPROTECTIVE AGENTS | HOECHST MARION ROUSSEL INC. (US) | 1997-01-07 | — | — | US | disclosed |
| US-5565579-A | NEUROPROTECTIVE AGENT | HOECHST MARION ROUSSEL INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0563916-B1 | (1H-Indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5319096-A | Neuroprotective agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0563916-A1 | (1H-Indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-10-06 | — | — | EP | disclosed |