SCHEMBL4110334

SCHEMBL4110334

Cc1cc(C(=O)c2ccccc2)cs1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.62
CA2 P00918 2/20 0.56
ALDH1A1 P00352 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ATM Q13315 1/20 0.52
NPC1 O15118 4/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 3/20 0.47
SRD5A2 P31213 1/20 0.47
HPGD P15428 4/20 0.47
HTT P42858 2/20 0.45
USP2 O75604 1/20 0.45
MAPK1 P28482 1/20 0.45
HPGDS O60760 1/20 0.44
PBRM1 Q86U86 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28542772 0.78 CA2 (0.57) CA2ALDH1A1L3MBTL1TDP1ATM
Benzophenone SCHEMBL28127869 0.78 ALDH1A1 (0.88) DAOALDH1A1L3MBTL1TDP1ATM
SCHEMBL131281 0.77
SCHEMBL6377804 0.77 CA2 (0.56) CA2ALDH1A1L3MBTL1TDP1ATM
SCHEMBL31287853 0.77 DAO (0.62) DAOCA2ALDH1A1L3MBTL1TDP1
SCHEMBL10367856 0.76 ATM (0.55) CA2ALDH1A1L3MBTL1TDP1ATM
Hydrochloric Acid SCHEMBL11001920 0.75 DAO (0.95) DAOALDH1A1L3MBTL1TDP1NPC1
Benzophenone SCHEMBL7454682 0.73 ALDH1A1 (0.88) DAOALDH1A1L3MBTL1TDP1ATM
Benzophenone SCHEMBL30537001 0.73 ALDH1A1 (1.00) DAOCA2ALDH1A1L3MBTL1TDP1
Benzophenone SCHEMBL6061130 0.73 ALDH1A1 (1.00) DAOCA2ALDH1A1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH DAO 256/4885CA2 77/4885ALDH1A1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.