Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285516 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL29763164 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL411173 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL14991107 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL441970 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL31710840 | 0.90 | ALDH1A1 (0.82) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL9741723 | 0.90 | ALDH1A1 (0.82) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL2172873 | 0.90 | ALDH1A1 (0.81) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL6896852 | 0.88 | ALDH1A1 (0.79) | ALDH1A1POLBKDM4EHPGDMAPK1 | |
| SCHEMBL6896845 | 0.88 | ALDH1A1 (0.79) | ALDH1A1POLBKDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530786-A | Film stripping liquid suitable for flexible circuit board and preparation method thereof | 深圳市天熙科技开发有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-110643670-A | Method for preparing D-glutamine by chemical enzyme method | 湖北新生源生物工程有限公司 | 2020-01-03 | — | — | CN | claimed |
| US-7723425-B2 | Pigment compositions with modified ATRP copolymer dispersants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | claimed |
| EP-1920773-A1 | Compositions for inhibition of anglogenesis | The Children's Medical Center Corporation (US) | 2008-05-14 | — | — | EP | claimed |
| EP-1586322-A2 | Compositions for inhibition of anglogenesis | The Children's Medical Center Corporation (US) | 2005-10-19 | — | — | EP | claimed |
| US-20040248820-A1 | Methods and compositions for inhibition of angiogenesis | D AMATO ROBERT J (US) | 2004-12-09 | — | — | US | claimed |
| US-20030191098-A1 | Methods and compositions for inhibition of angiogenesis | D AMATO ROBERT J (US) | 2003-10-09 | — | — | US | claimed |
| JP-2002513391-A | — | — | 2002-05-08 | — | — | JP | claimed |
| EP-0963200-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF ANGIOGENESIS | The Children's Medical Center Corporation (US) | 1999-12-15 | — | — | EP | claimed |
| WO-1998019649-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF ANGIOGENESIS | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-05-14 | — | — | WO | claimed |
| EP-0688211-A4 | METHODS AND COMPOSITIONS FOR INHIBITION OF ANGIOGENESIS | CHILDRENS MEDICAL CENTER (US) | 1997-05-21 | — | — | EP | claimed |
| US-5593990-A | Methods and compositions for inhibition of angiogenesis | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1997-01-14 | — | — | US | claimed |
| EP-0688211-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF ANGIOGENESIS | The Children's Medical Center Corporation (US) | 1995-12-27 | — | — | EP | claimed |
| WO-1994020085-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF ANGIOGENESIS | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1994-09-15 | — | — | WO | claimed |
| EP-4649963-A2 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| EP-3131588-B1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS INC (US) | 2025-11-05 | — | — | EP | disclosed |
| EP-4509184-A2 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2025-02-19 | — | — | EP | disclosed |
| US-4687817-A | REACTION WITH PHTHALOYLAMINO ACID OR DERIVATIVE, HYDRAZINE | NITTO BOSEKI CO. LTD. (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4604451-A | Novel functionalized resin derived from polyallylamine | NITTO BOSEKI CO., LTD. (JP) | 1986-08-05 | — | — | US | disclosed |
| EP-0154742-A2 | Novel functionalized resin derived from polyallylamine | NITTO BOSEKI CO., LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248820-A1 | Methods and compositions for inhibition of angiogenesis | PGF, PTGS1, PTGIS | ALDH1A1 436/4885POLB 2940/4885KDM4E 2121/4885 |
| US-20030191098-A1 | Methods and compositions for inhibition of angiogenesis | PGF, PTGS1, PTGIS | ALDH1A1 436/4885POLB 2940/4885KDM4E 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.