SCHEMBL411234

SCHEMBL411234

CC(=O)C(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL29038543 0.80 CES1 (0.41)
SCHEMBL70056 0.76 CA2 (0.41)
SCHEMBL2610839 0.76
SCHEMBL11351261 0.73
SCHEMBL16370918 0.72 LMNA (0.42)
SCHEMBL16821 0.72
SCHEMBL18906335 0.72
Trifluoroacetic Acid SCHEMBL28524351 0.71 TSHR (0.50)
SCHEMBL9577026 0.71
SCHEMBL11799633 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019164778-A1 PROCESS FOR PREPARING 1-ARYLSULFONYL-PYRROLIDINE-2-CARBOXAMIDE TRANSIENT RECEPTOR POTENTIAL CHANNEL ANTAGONIST COMPOUNDS AND CRYSTALLINE FORMS THEREOF GENENTECH, INC. (US) 2019-08-29 WO claimed
CN-118150554-A Application of chemiluminescent microarray chip 上海索昕生物科技有限公司 2024-06-07 CN disclosed
US-20240167062-A1 HYDROGEL SYSTEM FOR CONTROLLING OXYGEN CONCENTRATION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-05-23 US disclosed
CN-118010974-A Homogeneous phase chemiluminescence detection kit 科美博阳诊断技术(上海)有限公司 2024-05-10 CN disclosed
US-20240132508-A1 PROCESS FOR PREPARING BTK INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2024-04-25 US disclosed
WO-2024075124-A1 PEPTIDE-BASED NON-CRYSTALLINE MATERIALS AND COMPOSITIONS AND PROCESSES FOR OBTAINING SAME RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-04-11 WO disclosed
CN-113125699-B beta-hCG homogeneous phase chemiluminescence detection kit and application thereof 科美博阳诊断技术(上海)有限公司 2024-03-26 CN disclosed
EP-4334311-A1 PROCESS FOR PREPARING BTK INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-03-13 EP disclosed
CN-117074686-A Application of donor reagent in diagnosis of myocardial injury of subject 科美博阳诊断技术(上海)有限公司 2023-11-17 CN disclosed
CN-116754757-A Donor particle for homogeneous chemiluminescence analysis and application thereof 上海索昕生物科技有限公司 2023-09-15 CN disclosed
WO-2002074235-A2 HETEROCYCLIC COMPOUNDS FOR THERAPEUTIC USE J.B. CHEMICALS & PHARMACEUTICALS LTD (IN) 2002-09-26 WO disclosed
US-6403629-B2 1-(P-(METHYLSULFONAMIDO)PHENYL)-3-TRIFLUOROMETHYL-5-PHENYLPYRA ZOLONE AND DERIVATIVES; ANTIINFLAMMATORY AGENTS J.B. CHEMICAL AND PHARMACEUTICALS LIMITED (IN) 2002-06-11 US disclosed
US-20010047023-A1 New Heterocyclic compounds for therapeutic use J.B. CHEMICALS & PHARMACEUTICALS LIMITED 2001-11-29 US disclosed
EP-0839828-A1 Building blocks for DNA/PNA-Cooligomer BAYER AG (DE) 1998-05-06 EP disclosed
US-5300412-A Novel yellow and cyan couplers; excellent image storage stability FUJI PHOTO FILM CO., LTD. (JP) 1994-04-05 US disclosed
EP-0502424-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-01-19 EP disclosed
US-5238800-A Curls in direction of back coating side which has specified specific surface resistance KONICA CORPORATION (JP) 1993-08-24 US disclosed
EP-0502424-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-09-09 EP disclosed
EP-0491176-A1 Silver halide photographic light-sensitive material improved in anti-jamming property KONICA CORPORATION (JP) 1992-06-24 EP disclosed
EP-0021773-A1 Thiazolo (2,3-b) benzo (and azabenzo) thiazole derivatives, process for their preparation and pharmaceutical compositions containing them AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-07 EP disclosed