SCHEMBL70056

SCHEMBL70056

O=C(C(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CES1 P23141 1/20 0.32
FAAH O00519 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16402425 0.82 CA2 (0.37) CA2ALDH1A1POLBSMN1; SMN2
SCHEMBL5078106 0.82 THRB (0.33) CA2
SCHEMBL6151164 0.82 CA2 (0.32) CA2ALDH1A1
SCHEMBL2325979 0.79
SCHEMBL27560428 0.79
SCHEMBL4104149 0.79
SCHEMBL486188 0.79
SCHEMBL5081323 0.77 THRB (0.42)
SCHEMBL2138458 0.77
SCHEMBL12261955 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814348-B2 Oxidizing liquid media for chemical transformations UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-14 US claimed
CN-112346309-A Preparation method of durable anti-counterfeiting blue carbon powder 湖北尚彩新材料科技有限公司 2021-02-09 CN claimed
WO-2009019219-A2 METHODS OF USING A SOLVENT OR A FOAM BLOWING AGENT Solvay (Société Anonyme) (BE) 2009-02-12 WO claimed
EP-0580916-B1 N(1) substituted pyrazino [2,3-c]-1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals PRODESFARMA SA (ES) 1997-03-05 EP claimed
EP-0580916-A1 N(1) substituted pyrazino 2,3-c -1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals PRODESFARMA, S.A. (ES) 1994-02-02 EP claimed
CN-115108905-B Method for producing (Z) -trifluoromethaneenol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid 湖南大学 2025-04-08 CN disclosed
CN-115710637-B Extractant and application thereof in extraction of lithium, rubidium and cesium 中国科学院过程工程研究所 2025-03-11 CN disclosed
US-11911371-B2 Pyridine and pyrazine derivative for the treatment of chronic bronchitis NOVARTIS AG (CH) 2024-02-27 US disclosed
US-20240058315-A1 Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis NOVARTIS AG (CH) 2024-02-22 US disclosed
US-11814348-B2 Oxidizing liquid media for chemical transformations UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-14 US disclosed
US-11551827-B2 Perfluorinated 1-alkoxypropenes in dielectric fluids and electrical devices 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-01-10 US disclosed
CN-115108905-A Method for generating (Z) -trifluoromethane enol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid 湖南大学 2022-09-27 CN disclosed
US-5057586-A Fluoropolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-15 US disclosed
US-4973714-A ADDITION POLYMERS, FLUOROPOLYMERS, HEAT RESISTANCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-27 US disclosed
US-4810806-A FROM A HALOETHYL CARBOXYLATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-07 US disclosed
EP-0301881-A1 Halogenated 1,3-dioxolanes and derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-01 EP disclosed
US-4343742-A CYCLIZATION OF MONOETHERS CONTAINING CARBONYL, AMMONIUM OR ALKALI FLUORIDE HOECHST AKTIENGESELLSCHAFT 1982-08-10 US disclosed
US-4005104-A CHEMICAL INTERMEDIATE FOR PERFLUOROBIACETYL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-25 US disclosed
US-4005104-A CHEMICAL INTERMEDIATE FOR PERFLUOROBIACETYL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-25 US disclosed
US-3985810-A METALLIC CATALYST; REACTING A CARBOXYLIC ACID FLUORIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11551827-B2 Perfluorinated 1-alkoxypropenes in dielectric fluids and electrical devices AFF1, AFF2, AFF4 CA2 3047/4885ALDH1A1 331/4885POLB 2311/4885
US-11911371-B2 Pyridine and pyrazine derivative for the treatment of chronic bronchitis CFTR, OPRK1, CHRM3 CA2 3580/4885ALDH1A1 2546/4885POLB 2917/4885
US-20240058315-A1 Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis CFTR, OPRK1, CHRM3 CA2 3076/4885ALDH1A1 2914/4885POLB 2724/4885
US-11814348-B2 Oxidizing liquid media for chemical transformations HAO2, LPO, DUOX1 CA2 143/4885ALDH1A1 785/4885POLB 190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.