Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.44 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381559 | 0.87 | ALDH1A1 (0.59) | EPHX2KDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL17941592 | 0.79 | TRPA1 (0.50) | RHOCRHOAAR | |
| SCHEMBL3786166 | 0.78 | AR (0.50) | RHOCRHOALMNAALDH1A1MAPK1 | |
| SCHEMBL12041409 | 0.78 | KHK (0.43) | LMNAMAPK1AR | |
| SCHEMBL12947525 | 0.77 | EPHX2 (0.40) | EPHX2RHOCRHOAKDM4ELMNA | |
| SCHEMBL12042459 | 0.77 | HTR7 (0.42) | EPHX2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL381966 | 0.77 | KHK (0.42) | LMNAMAPK1AR | |
| SCHEMBL12042460 | 0.76 | HTR7 (0.51) | EPHX2RHOCRHOALMNAMAPT | |
| SCHEMBL15354211 | 0.76 | EPHX2 (0.40) | EPHX2KDM4ELMNAAR | |
| SCHEMBL14562834 | 0.76 | RHOC (0.58) | EPHX2RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408742-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010115688-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-10-14 | — | — | WO | disclosed |