SCHEMBL4113303

SCHEMBL4113303

CC(C)Cc1nc2ccccc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.65
MAPK1 P28482 2/20 0.60
ALPL P05186 1/20 0.60
KDM4E B2RXH2 1/20 0.59
MAPT P10636 1/20 0.59
POLB P06746 1/20 0.59
PKM P14618 1/20 0.57
GAA P10253 1/20 0.56
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP1A2 P05177 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.55
TP53 P04637 1/20 0.55
KMT2A Q03164 1/20 0.55
BCHE P06276 1/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989354 0.89 ALOX12 (0.56) DDAH1MAPK1ALPLKDM4EMAPT
SCHEMBL30207649 0.86 DDAH1 (0.61) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL2680248 0.86 CYP3A4 (0.64) DDAH1MAPK1ALPLPOLBPKM
SCHEMBL13050694 0.86 CYP3A4 (0.64) DDAH1MAPK1ALPLPOLBPKM
SCHEMBL133478 0.86 DDAH1 (0.61) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL20646170 0.86 DDAH1 (0.61) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL8025715 0.86 DDAH1 (0.61) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL20677814 0.85 DDAH1 (0.63) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL4106172 0.84 DDAH1 (0.64) DDAH1MAPK1ALPLKDM4EPOLB
SCHEMBL6346692 0.83 DDAH1 (0.57) DDAH1MAPK1ALPLKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428260-B1 Metal surface treatment agents SANWA LAB LTD (JP) 2000-01-05 EP claimed
EP-0562187-B1 Process for production of copper through-hole printed wiring boards SANWA LAB LTD (JP) 1996-01-10 EP claimed
US-5275694-A Printed circuits with copper through holes, negative patterns, photoresists, lamination, dipping and etching SANWA LABORATORY LTD. (JP) 1994-01-04 US claimed
EP-0562187-A1 Process for production of copper through-hole printed wiring boards SANWA LABORATORY LTD. (JP) 1993-09-29 EP claimed
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP claimed
US-12029739-B2 SHP2 inhibitor and use thereof KANAPH THERAPEUTICS INC. (KR) 2024-07-09 US disclosed
US-12029739-B2 SHP2 inhibitor and use thereof KANAPH THERAPEUTICS INC. (KR) 2024-07-09 US disclosed
CN-116810216-A Water-soluble pre-flux and surface treatment method 株式会社田村制作所 2023-09-29 CN disclosed
EP-3675858-B1 IMIDAZO[1,5-A]PYRAZINE COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION OPTIKIRA LLC (US) 2023-04-26 EP disclosed
EP-3397629-B1 METALLOENZYME INHIBITOR COMPOUNDS NQP 1598 LTD (KY) 2023-04-19 EP disclosed
US-20230043159-A1 MATRIPTASE 2 INHIBITORS AND USES THEREOF DISC MEDICINE, INC. 2023-02-09 US disclosed
US-20220395487-A1 RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME UNIV YALE (US) 2022-12-15 US disclosed
EP-0791671-B1 Surface treating agent for copper or copper alloy SHIKOKU CHEM (JP) 1999-06-16 EP disclosed
US-5795409-A MIXTURE OF A (BENZ)IMIDAZOLE COMPOUND, CHELATE COMPOUND AND IRON SHIKOKU CHEMICALS CORPORATION (JP) 1998-08-18 US disclosed
EP-0791671-A1 Surface treating agent for copper or copper alloy SHIKOKU CHEMICALS CORPORATION (JP) 1997-08-27 EP disclosed
EP-0562187-B1 Process for production of copper through-hole printed wiring boards SANWA LAB LTD (JP) 1996-01-10 EP disclosed
US-5348590-A Surface treating agent for copper or copper alloys HITACHI, LTD. (JP) 1994-09-20 US disclosed
US-5275694-A Printed circuits with copper through holes, negative patterns, photoresists, lamination, dipping and etching SANWA LABORATORY LTD. (JP) 1994-01-04 US disclosed
EP-0562187-A1 Process for production of copper through-hole printed wiring boards SANWA LABORATORY LTD. (JP) 1993-09-29 EP disclosed
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029739-B2 SHP2 inhibitor and use thereof PTPN1, PTPN5, PTPN2 DDAH1 2242/4885MAPK1 272/4885ALPL 3046/4885
US-20230043159-A1 MATRIPTASE 2 INHIBITORS AND USES THEREOF MMP7, MATR3, SPINT2 DDAH1 2237/4885MAPK1 2988/4885ALPL 2209/4885
US-20220395487-A1 RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME MAVS, HAVCR2, IRF3 DDAH1 2400/4885MAPK1 3608/4885ALPL 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.