Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 7/20 | 0.37 |
| ▸ | CES1 | P23141 | 7/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109757 | 0.83 | CES2 (0.41) | ALDH1A1CYP1A2CYP2C9CES2CES1 | |
| SCHEMBL4103684 | 0.79 | CNR1 (0.42) | ALDH1A1CYP1A2CYP2C9CHRM2CES2 | |
| SCHEMBL6518724 | 0.78 | CES2 (0.57) | ALDH1A1CES2CES1HTT | |
| SCHEMBL4104969 | 0.78 | CYP1A2 (0.41) | ALDH1A1CYP1A2CYP2C9CHRM2AKR1C3 | |
| SCHEMBL4114438 | 0.78 | PTPN1 (0.41) | ALDH1A1CYP1A2CYP2C9CHRM2CES2 | |
| Bromide SCHEMBL2097705 | 0.77 | CES2 (0.56) | ALDH1A1CES2CES1HTT | |
| SCHEMBL4109111 | 0.76 | CES2 (0.38) | ALDH1A1CYP1A2CYP2C9CHRM2CES2 | |
| SCHEMBL4103736 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C9CES2CES1 | |
| SCHEMBL4109795 | 0.76 | CES2 (0.38) | ALDH1A1CYP1A2CYP2C9CHRM2CES2 | |
| SCHEMBL1155548 | 0.74 | CES2 (0.55) | ALDH1A1CES2CES1HTTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | ALDH1A1 195/4885CYP1A2 137/4885CYP2C9 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.