Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 10/20 | 0.42 |
| ▸ | CTSK | P43235 | 9/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117611 | 1.00 | REN (0.46) | RENDRD1CTSSCTSKCTSB | |
| SCHEMBL4112023 | 0.91 | REN (0.48) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4112030 | 0.91 | REN (0.48) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4105832 | 0.91 | REN (0.49) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4105826 | 0.91 | REN (0.49) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4739186 | 0.90 | ACE (0.52) | DRD1CTSSCTSKCTSBACE | |
| SCHEMBL4801481 | 0.90 | ACE (0.52) | DRD1CTSSCTSKCTSBACE | |
| SCHEMBL4112720 | 0.88 | ALOX15 (0.54) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4112727 | 0.88 | ALOX15 (0.54) | RENCTSSCTSKCTSBACE | |
| SCHEMBL4111125 | 0.87 | ALOX15 (0.56) | RENDRD1CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239941-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-09-24 | — | — | US | disclosed |
| EP-1993995-A1 | AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007104959-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239941-A1 | AMINO ACID DERIVATIVES | DRD2, SLC1A5, DAO | REN 884/4885DRD1 18/4885CTSS 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.