Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739186 | 1.00 | ACE (0.52) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL4117611 | 0.90 | REN (0.46) | ACEPTPN1PPARGCTSSCTSK | |
| SCHEMBL4117607 | 0.90 | REN (0.46) | ACEPTPN1PPARGCTSSCTSK | |
| SCHEMBL585379 | 0.88 | SCN9A (0.47) | ACEPPARGCTSSCTSKCTSB | |
| SCHEMBL4801162 | 0.87 | ACE (0.52) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL4801147 | 0.87 | ACE (0.52) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL1217701 | 0.87 | ALOX15 (0.57) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL27406863 | 0.86 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL1216618 | 0.85 | ACE (0.55) | ACEITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL1214530 | 0.85 | DRD1 (0.42) | ACEPTPN1PPARGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079387-A1 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-07-03 | — | — | WO | disclosed |