SCHEMBL4117728

SCHEMBL4117728

CCCCOC([SiH3])(OCCCC)C(CC)(OCCCC)OCCCC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8666264 0.74 ALDH1A1 (0.31) ADRB2ADRB1ADRB3
SCHEMBL8462442 0.73 ADRB2 (0.38) ADRB2ADRB1ADRB3ATMCYP3A4
SCHEMBL28668734 0.72
SCHEMBL449530 0.72 ADRB2 (0.41) ADRB2ADRB1ADRB3ATMCYP3A4
SCHEMBL3886637 0.70 ADRB2 (0.39) ADRB2ADRB1ADRB3ATMCYP3A4
SCHEMBL28918138 0.70 HPGD (0.32) TSHR
SCHEMBL15061302 0.70 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL6420163 0.70 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL10348467 0.69
SCHEMBL9497575 0.67 ADRB2 (0.41) ADRB2ADRB1ADRB3ATMCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090078154-A1 Coating Agent for Optical Instrument KAO CORPORATION (JP) 2009-03-26 US disclosed
EP-1868012-A1 COATING AGENT FOR OPTICAL INSTRUMENT Kao Corporation (JP) 2007-12-19 EP disclosed
EP-0526975-B1 Coating composition for optical plastic moldings ITOH OPTICAL IND (JP) 1995-07-26 EP disclosed