SCHEMBL28918138

SCHEMBL28918138

C=CC(CC)(OCCCC)C([SiH3])(OCCCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537821 0.74 TSHR (0.38) HPGDTSHR
SCHEMBL4117728 0.70 ADRB2 (0.33) TSHR
SCHEMBL7935122 0.68 TSHR (0.34) HPGDTSHR
SCHEMBL12826538 0.67 TSHR (0.39) HPGDTSHR
SCHEMBL7937308 0.67 TSHR (0.38) HPGDTSHR
SCHEMBL3677726 0.67 TSHR (0.36) HPGDTSHR
SCHEMBL8462442 0.66 ADRB2 (0.38) TSHR
SCHEMBL449530 0.65 ADRB2 (0.41) HPGDTSHR
SCHEMBL3886637 0.64 ADRB2 (0.39) TSHR
SCHEMBL27323127 0.63 TSHR (0.39) HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115349090-A Diagnostic device 3M创新有限公司 2022-11-15 CN disclosed