Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396213 | 1.00 | USP7 (0.34) | USP7GRIN2BGRIN1GCGRTGFBR1 | |
| SCHEMBL2301732 | 0.89 | MET (0.32) | USP7GCGR | |
| SCHEMBL2302651 | 0.89 | PGR (0.36) | USP7GRIN2BGRIN1GCGR | |
| SCHEMBL2300057 | 0.86 | PGR (0.35) | USP7GRIN2BGRIN1GCGRTGFBR1 | |
| SCHEMBL2299477 | 0.86 | PGR (0.35) | USP7GRIN2BGRIN1GCGRTGFBR1 | |
| SCHEMBL2300197 | 0.83 | PGR (0.34) | GRIN2BKDM4CKMO | |
| SCHEMBL16503270 | 0.80 | GRIN2B (0.33) | GRIN2BGRIN1 | |
| SCHEMBL2298097 | 0.80 | GRIN2B (0.33) | GRIN2BGRIN1 | |
| SCHEMBL2301131 | 0.78 | PDGFRB (0.38) | — | |
| SCHEMBL16503269 | 0.78 | EGFR (0.33) | USP7GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312975-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | YANG ZHE (US) | 2011-12-22 | — | — | US | disclosed |
| US-20090253737-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253737-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | TNNC1, TNNI3, TNNT2 | USP7 3474/4885GRIN2B 3318/4885GRIN1 2428/4885 |
| US-20110312975-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | TNNC1, TNNI3, TNNT2 | USP7 3466/4885GRIN2B 3416/4885GRIN1 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.