Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115080 | 0.98 | HRH3 (0.39) | HRH3L3MBTL1LMNAMAPTANPEP | |
| Hydrochloric Acid SCHEMBL3669525 | 0.86 | ALOX15 (0.43) | ALOX15 | |
| SCHEMBL15559429 | 0.84 | HRH3 (0.46) | HRH3L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL15559428 | 0.84 | HRH3 (0.46) | HRH3L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL10447876 | 0.82 | ALOX15 (0.59) | ALDH1A1ALOX15 | |
| SCHEMBL4119651 | 0.82 | ALOX15 (0.40) | HRH3L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL3091684 | 0.80 | L3MBTL1 (0.42) | HRH3L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL23278171 | 0.78 | HRH3 (0.39) | HRH3L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL1264196 | 0.78 | POLB (0.41) | POLBANPEPERAP2ALOX15 | |
| SCHEMBL10609723 | 0.78 | HRH3 (0.48) | HRH3L3MBTL1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | IL2, CASP2, MAVS | HRH3 1086/4885L3MBTL1 3415/4885LMNA 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.