⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482032 | 0.97 | — | — | |
| SCHEMBL183045 | 0.84 | MKNK1 (0.45) | — | |
| SCHEMBL242388 | 0.78 | FFAR1 (0.39) | — | |
| SCHEMBL2399197 | 0.78 | LTA4H (0.63) | — | |
| SCHEMBL8722526 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL241799 | 0.77 | — | — | |
| SCHEMBL41775 | 0.75 | TSHR (0.67) | — | |
| SCHEMBL8713097 | 0.75 | ENPP2 (0.42) | — | |
| SCHEMBL320687 | 0.73 | CALM1 (0.44) | — | |
| SCHEMBL6576818 | 0.73 | GFER (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5981 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108698-A | Beta-carbonyl sulfinolactone compound and preparation method thereof | 华中师范大学 | 2024-05-31 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| WO-2024101411-A1 | CURABLE COMPOSITION FOR ORGANIC EL ELEMENTS, CURED PRODUCT FOR ORGANIC EL ELEMENTS AND METHOD FOR PRODUCING SAME, ORGANIC EL ELEMENT, AND POLYMER | JSR株式会社 | 2024-05-16 | — | — | WO | claimed |
| CN-118026957-A | Three-component coupling method for aromatic trifluoroalkyl compound, conjugated olefin and nucleophilic reagent | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| CN-117903107-A | [ (1-Sulfone-2-sulfinate) ethyl ] arene compound and preparation method thereof | 华中师范大学 | 2024-04-19 | — | — | CN | claimed |
| US-20240116903-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2024-04-11 | — | — | US | claimed |
| EP-4347568-A1 | HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2024-04-10 | — | — | EP | claimed |
| CN-117813084-A | Bruise and filler compositions and methods of use | 阿拉斯廷护肤品股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115725110-B | Silicone resin modified polybenzoxazine aerogel and preparation method thereof | 航天特种材料及工艺技术研究所 | 2024-03-26 | — | — | CN | claimed |
| US-20240092757-A1 | HETEROARYL DIAMIDE IRE1/XBP1s ACTIVATORS | THE SCRIPPS RESEARCH INSTITUTE | 2024-03-21 | — | — | US | claimed |
| US-4443436-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-04-17 | — | — | US | claimed |
| EP-0027948-B1 | TETRAHYDRO-FLUORENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | MERCK & CO. INC. (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0080975-A1 | Photosensitive polymers | CIBA-GEIGY AG (CH) | 1983-06-08 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| US-4317922-A | [(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives | MERCK & CO., INC. (US) | 1982-03-02 | — | — | US | claimed |
| US-4316043-A | ANTIEDEMIC AGENTS | MERCK & CO., INC. (US) | 1982-02-16 | — | — | US | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | claimed |
| EP-0027948-A1 | Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof | MERCK & CO. INC. (US) | 1981-05-06 | — | — | EP | claimed |