Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122697 | 0.80 | SOAT1 (0.39) | PTPN1 | |
| SCHEMBL4112090 | 0.80 | PTPN1 (0.64) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL3913372 | 0.78 | PTPN1 (0.55) | PTPN1POLBMAOAMAOB | |
| SCHEMBL5373635 | 0.67 | PTPN1 (0.54) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL29956932 | 0.66 | PTPN1 (0.68) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL9958482 | 0.65 | HTT (0.41) | PTPN1MEN1KMT2A | |
| SCHEMBL1997471 | 0.64 | PTPN1 (0.61) | PTPN1POLBMAOAMAOB | |
| SCHEMBL5166422 | 0.64 | AKR1B10 (0.51) | PTPN1MEN1KMT2AMAOA | |
| SCHEMBL5165720 | 0.63 | AKR1B10 (0.54) | PTPN1MEN1KMT2AMAOA | |
| SCHEMBL23887130 | 0.62 | PTPN1 (0.72) | PTPN1MEN1POLBKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | claimed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | claimed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | GNPAT, HOGA1, NQO1 | PTPN1 2770/4885MEN1 3741/4885POLB 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.