Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 4/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121887 | 0.80 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL4111430 | 0.73 | PTPN1 (0.51) | PTPN1 | |
| SCHEMBL3913372 | 0.72 | PTPN1 (0.55) | PTPN1ACHE | |
| SCHEMBL4112090 | 0.69 | PTPN1 (0.64) | PTPN1 | |
| SCHEMBL3968214 | 0.65 | MEN1 (0.46) | SOAT1SOAT2PTPN1HSP90AA1ACHE | |
| SCHEMBL5373635 | 0.59 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL1997471 | 0.59 | PTPN1 (0.61) | PTPN1ACHE | |
| SCHEMBL23887130 | 0.57 | PTPN1 (0.72) | PTPN1 | |
| SCHEMBL15697880 | 0.57 | PTPN1 (0.44) | PTPN1 | |
| SCHEMBL5708656 | 0.56 | PTPN1 (1.00) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | claimed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | claimed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | GNPAT, HOGA1, NQO1 | SOAT1 1141/4885SOAT2 1171/4885PTPN1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.