SCHEMBL4122942

SCHEMBL4122942

C=C(C)C(=O)Oc1ccc(C(CC)c2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.55
KMT2A Q03164 3/20 0.48
ATM Q13315 1/20 0.48
ESR1 P03372 1/20 0.46
HIF1A Q16665 1/20 0.46
FFAR1 O14842 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
CYP17A1 P05093 1/20 0.40
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FAAH O00519 1/20 0.38
AKR1C3 P42330 3/20 0.38
AKR1C2 P52895 3/20 0.38
AKR1C1 Q04828 1/20 0.38
PTGS1 P23219 1/20 0.38
MEN1 O00255 1/20 0.37
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4332836 0.94 ELANE (0.50) ELANEKMT2AATMESR1HIF1A
SCHEMBL819794 0.85 ALDH1A1 (0.54) ELANEKMT2AATMESR1HIF1A
SCHEMBL18061417 0.82 ELANE (0.57) ELANEKMT2AATMESR1HIF1A
SCHEMBL9699736 0.82 LMNA (0.53) ELANEKMT2AESR1HIF1AFFAR1
SCHEMBL25926109 0.82 ELANE (0.57) ELANEKMT2AATMESR1HIF1A
Butane SCHEMBL15309676 0.82 ELANE (0.61) ELANEKMT2AATMESR1HIF1A
SCHEMBL56436 0.82 ELANE (0.69) ELANEKMT2AATMALDH1A1POLB
SCHEMBL7259972 0.81 ESR1 (0.47) ELANEKMT2AESR1HIF1AFFAR1
SCHEMBL19017564 0.81 ELANE (0.56) ELANEKMT2AATMESR1HIF1A
SCHEMBL4594842 0.81 ELANE (0.56) ELANEKMT2AATMESR1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170261766-A1 CONTACT LENS WITH FLEXIBLE CENTER AND RIGID PERIPHERY THOMPSON VANCE M (US) 2017-09-14 US claimed
US-7097301-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-08-29 US claimed
EP-1546984-A1 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2005-06-29 EP claimed
US-20040179167-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-09-16 US claimed
WO-2004023374-A9 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES IN (US) 2004-04-29 WO claimed
WO-2004023374-A1 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES, INC. (US) 2004-03-18 WO claimed
US-20040046931-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-03-11 US claimed
US-6682872-B2 Comprises acrylic acid-acrylonitrile-butadiene terpolymer binder; for protective/passivative coatings, defect repair in ceramic and thin film products within printed circuits; solvent-free INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-01-27 US claimed
US-20030138733-A1 UV-curable compositions and method of use thereof in microelectronics INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-07-24 US claimed
CN-116600766-A Dental composition, kit and method for use as restorative material for replacement of dental amalgam SDI有限公司 2023-08-15 CN disclosed
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
CN-114423591-A Post-curing method for 3D printed light modeling 株式会社松风 2022-04-29 CN disclosed
CN-113993905-A Method for setting use condition of polymerization catalyst, method for setting polymerization condition, and method for producing optical material 三井化学株式会社 2022-01-28 CN disclosed
CN-107949584-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2021-04-27 CN disclosed
EP-0379146-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1990-07-25 EP disclosed
EP-0295012-A2 Process for the production of formed article of aromatic vinyl resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-12-14 EP disclosed
US-4774035-A WEAR RESISTANCE CAMELOT INDUSTRIES CORPORATION (US) 1988-09-27 US disclosed
US-4273799-A POLYFUNCTIONAL MONOMERS CONTAINING (METH)ACRYLOYLOXY GROUPS MITSUBISHI RAYON CO., LTD. (JP) 1981-06-16 US disclosed
US-4273802-A POLYFUNCTIONAL MONOMERS CONTAINING (METH)ACRYLOYLOXY GROUPS MITSUBISHI RAYON CO., LTD. (JP) 1981-06-16 US disclosed
US-4199421-A Coating composition and a method for producing a synthetic resin molded product having an abrasion resistant surface MITSUBISHI RAYON COMPANY, LIMITED (JP) 1980-04-22 US disclosed