SCHEMBL412323

SCHEMBL412323

CSCCC(NC(=O)C(N)CO)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(=O)NC(CS)C(=O)NC(CO)C(=O)NCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.42
▸ CALCR P30988 3/20 0.40
▸ GRPR P30550 1/20 0.36
▸ FNTA P49354 6/20 0.36
▸ FNTB P49356 6/20 0.36
▸ PGGT1B P53609 2/20 0.36
▸ KEAP1 Q14145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412324 1.00 APLNR (0.42) APLNRCALCRGRPRFNTAFNTB
SCHEMBL415551 0.97 APLNR (0.42) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL415550 0.97 APLNR (0.42) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL414401 0.95 APLNR (0.41) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL414400 0.95 APLNR (0.41) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL416410 0.90 OPRM1 (0.39) APLNR
SCHEMBL416409 0.90 OPRM1 (0.39) APLNR
SCHEMBL31256943 0.84 OPRM1 (0.42) —
SCHEMBL29616320 0.83 FNTA (0.45) FNTAFNTBPGGT1B
SCHEMBL29941145 0.82 CCKAR (0.42) CALCRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120020878-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2012-01-26 — — US disclosed
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