Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416410 | 1.00 | OPRM1 (0.39) | OPRM1OPRD1OPRK1PTGS1GSTK1 | |
| SCHEMBL31258095 | 0.92 | EGFR (0.40) | OPRM1OPRD1OPRK1EGFRPTPN1 | |
| SCHEMBL31257976 | 0.92 | EGFR (0.40) | OPRM1OPRD1OPRK1EGFRPTPN1 | |
| SCHEMBL414400 | 0.91 | APLNR (0.41) | OPRM1OPRD1EGFRAPLNR | |
| SCHEMBL414401 | 0.91 | APLNR (0.41) | OPRM1OPRD1EGFRAPLNR | |
| SCHEMBL31256943 | 0.90 | OPRM1 (0.42) | OPRM1OPRD1OPRK1EGFRPTPN1 | |
| SCHEMBL415551 | 0.90 | APLNR (0.42) | APLNR | |
| SCHEMBL415550 | 0.90 | APLNR (0.42) | APLNR | |
| SCHEMBL412323 | 0.90 | APLNR (0.42) | APLNR | |
| SCHEMBL412324 | 0.90 | APLNR (0.42) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | disclosed |