SCHEMBL415550

SCHEMBL415550

CSCCC(NC(=O)C(CO)NC(=O)C(N)CS)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(=O)NC(CS)C(=O)NC(CO)C(=O)NCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.42
▸ CALCR P30988 3/20 0.42
▸ FNTA P49354 10/20 0.40
▸ FNTB P49356 10/20 0.40
▸ PGGT1B P53609 6/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL415551 1.00 APLNR (0.42) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL412324 0.97 APLNR (0.42) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL412323 0.97 APLNR (0.42) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL414400 0.95 APLNR (0.41) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL414401 0.95 APLNR (0.41) APLNRCALCRFNTAFNTBPGGT1B
SCHEMBL416409 0.90 OPRM1 (0.39) APLNR
SCHEMBL416410 0.90 OPRM1 (0.39) APLNR
SCHEMBL31256943 0.84 OPRM1 (0.42) —
SCHEMBL29519342 0.84 APLNR (0.40) APLNR
SCHEMBL29616320 0.83 FNTA (0.45) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120020878-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2012-01-26 — — US disclosed
CN-102264349-A Sphingolipid activator protein C and related protein and peptide fusogenic properties for transmembrane drug delivery systems — 2011-11-30 — — CN disclosed
EP-2365796-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS Children's Hospital Medical Center (US) 2011-09-21 — — EP disclosed
WO-2010053489-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2010-05-14 — — WO disclosed
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