SCHEMBL412378

SCHEMBL412378

FC(F)(F)Nc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
TDP1 Q9NUW8 4/20 0.45
HSD17B10 Q99714 4/20 0.45
CTSD P07339 1/20 0.45
TSHR P16473 4/20 0.43
PTGS2 P35354 2/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
MAPK1 P28482 1/20 0.43
HTR2B P41595 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 3/20 0.42
CYP3A4 P08684 3/20 0.41
IDO1 P14902 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7518126 0.97 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Water SCHEMBL6244808 0.97 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Fluoride SCHEMBL5178837 0.97 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Iodide SCHEMBL30460417 0.97 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Hydrochloric Acid SCHEMBL1768868 0.97 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Boric Acid SCHEMBL28518790 0.90 MAPT (0.41) ALDH1A1TDP1HSD17B10CTSDTSHR
Boric Acid SCHEMBL28518789 0.90 MAPT (0.41) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL7003928 0.85 KIF11 (0.50) ALDH1A1TDP1HSD17B10MAPK1MAPT
Acetoacetic Acid SCHEMBL7876692 0.79 MAPT (0.48) ALDH1A1HSD17B10TSHRL3MBTL1MAPT
SCHEMBL6226934 0.79 MGLL (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094389-A Perovskite material, perovskite layer, preparation method of perovskite layer, perovskite solar cell and photovoltaic module 2026-05-26 CN claimed
CN-120504610-B Method for continuously preparing m-trifluoromethyl aniline diazonium salt 山东师范大学 2026-05-19 CN claimed
WO-2025125665-A1 FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-06-19 WO claimed
CN-114420852-B Preparation method of pure-phase RP perovskite film 河北工业大学 2025-05-27 CN claimed
CN-120040314-A Method for continuously preparing m-trifluoromethyl acetophenone oxime 山东师范大学实验厂有限公司 2025-05-27 CN claimed
CN-119930443-A Method for synthesizing trifluoromethyl substituted aniline by using tetradentate platinum complex as photocatalyst 九洲药业(杭州)有限公司 2025-05-06 CN claimed
CN-119869420-A Trifluoromethyl aniline cauldron raffinate resourceful utilization equipment 安徽鑫泰新材料有限公司 2025-04-25 CN claimed
CN-114824092-B Solar cell based on quasi-two-dimensional perovskite and preparation method thereof 北京炎和科技有限公司 2025-04-18 CN claimed
CN-119684069-A Method for preparing beta-trichloromethyl butyl ester or amide 中国科学院大连化学物理研究所 2025-03-25 CN claimed
CN-119431183-A Process for continuously synthesizing m-trifluoromethyl acetophenone oxime by adopting microchannel reactor 中国计量大学 2025-02-14 CN claimed
EP-0103919-A2 Process for producing substituted asymmetric ureas ENICHEM ANIC S.p.A. (IT) 1984-03-28 EP claimed
US-4405357-A Herbicidal 3-isoxazolidinones and hydroxamic acids FMC CORPORATION (US) 1983-09-20 US claimed
EP-0012385-B1 DIBENZ(B,F)(1,4)OXAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS Chugai Seiyaku Kabushiki Kaisha (JP) 1983-02-16 EP claimed
US-4366309-A MACROLACTONES SCHERING CORPORATION (US) 1982-12-28 US claimed
EP-0013376-B1 ISOXAZOLE DERIVATIVE, PROCESS FOR ITS PREPARATION AND COMPOSITION CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-19 EP claimed
EP-0003766-A1 N-(omega-chloroalcanoyl)-N'-trifluoromethylphenyl-urea, preparation thereof and use thereof as plant-protecting agents BAYER AG (DE) 1979-09-05 EP claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-3978049-A Process for the preparation of hydrazine compounds PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-31 US claimed
US-3972878-A Method for preparing azines and hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed