Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412378 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| Water SCHEMBL6244808 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| Iodide SCHEMBL30460417 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7518126 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1768868 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| Fluoride SCHEMBL5178837 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6226934 | 0.80 | MGLL (0.50) | KIF11HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL8068086 | 0.79 | KIF11 (0.52) | KIF11ALDH1A1HSD17B10TAAR1CYP1A2 | |
| SCHEMBL12205824 | 0.76 | IDH2 (0.44) | KIF11ALDH1A1PTPN1PTPN11TAAR1 | |
| Boric Acid SCHEMBL28518790 | 0.76 | MAPT (0.41) | ALDH1A1HDAC1HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100414329-C | S-shaped type curved optical waveguide and optical device | HITACHI CHEMICAL CO LTD (JP) | 2008-08-27 | — | — | CN | disclosed |
| CN-1938620-A | S-shaped type curved optical waveguide and optical device | HITACHI CHEMICAL CO LTD (JP) | 2007-03-28 | — | — | CN | disclosed |
| EP-1268413-A2 | SUBSTITUTED BIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070678-A2 | SUBSTITUTED BIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |