Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903775 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL13903782 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL4124094 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL21382193 | 0.95 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL13903766 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL13903777 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL2616645 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL5074195 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL2832986 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL | |
| SCHEMBL17366592 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15TSHRTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12599615-B2 | Use of carotenoids in the treatment of senescence-related diseases | GAT THERAPEUTICS, S.L. (ES) | 2026-04-14 | — | — | US | disclosed |
| EP-4218746-A1 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | Gat Therapeutics S.L. (ES) | 2023-08-02 | — | — | EP | disclosed |
| EP-4144338-A2 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | ALGAKTIV, S.L. (ES) | 2023-03-08 | — | — | EP | disclosed |
| CN-115715804-A | Use of carotenoids in the treatment of age-related disorders | 阿尔加克蒂夫有限公司 | 2023-02-28 | — | — | CN | disclosed |
| US-20220395515-A1 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | ALGAKTIV, S.L. (ES) | 2022-12-15 | — | — | US | disclosed |
| US-20220152062-A1 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | GAT THERAPEUTICS, S.L. (ES) | 2022-05-19 | — | — | US | disclosed |
| EP-3705109-A1 | CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | Greenaltech, S.L. (ES) | 2020-09-09 | — | — | EP | disclosed |
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LY CORED LTD. (IL) | 2009-03-12 | — | — | US | disclosed |
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LY CORED LTD. (IL) | 2009-03-12 | — | — | US | disclosed |
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LY CORED LTD. (IL) | 2009-03-12 | — | — | US | disclosed |
| EP-1937288-A2 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | Lycored Ltd. (IL) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007043046-A2 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LYCORED LTD. (IL) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007043046-A2 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LYCORED LTD. (IL) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220152062-A1 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | BCL2, BCL2A1, BCL2L1 | ALDH1A1 3785/4885ALOX15 597/4885TSHR 3483/4885 |
| US-20220395515-A1 | USE OF CAROTENOIDS IN THE TREATMENT OF SENESCENCE-RELATED DISEASES | BCL2, BCL2A1, BCL2L1 | ALDH1A1 3785/4885ALOX15 597/4885TSHR 3483/4885 |
| US-12599615-B2 | Use of carotenoids in the treatment of senescence-related diseases | MCL1, BCLAF1, BCL2A1 | ALDH1A1 1904/4885ALOX15 1324/4885TSHR 4119/4885 |
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | DOHH, BBOX1, TXN2 | ALDH1A1 27/4885ALOX15 65/4885TSHR 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.