Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727281 | 0.86 | ABCG2 (0.83) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL774317 | 0.86 | ADORA3 (0.72) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL30082745 | 0.84 | MEN1 (0.84) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL30082748 | 0.84 | ABCG2 (0.74) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL28980660 | 0.83 | XDH (0.74) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL16894630 | 0.82 | TUBB4A (0.70) | ABCB1ABCG2MEN1KMT2APOLB | |
| Hexamethoxyflavone SCHEMBL987569 | 0.82 | MEN1 (0.74) | ABCB1ABCG2MEN1KMT2APOLB | |
| Hexamethoxyflavone SCHEMBL30232628 | 0.82 | MEN1 (0.74) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL16894654 | 0.82 | ADORA3 (0.72) | ABCB1ABCG2MEN1KMT2APOLB | |
| SCHEMBL31287150 | 0.82 | ADORA3 (0.72) | ABCB1ABCG2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |