Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.62 |
| ▸ | CCR5 | P51681 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853358 | 0.83 | OPRM1 (0.60) | OPRM1CHRM2CHRM3CCR5KCNH2 | |
| SCHEMBL4199351 | 0.83 | OPRM1 (0.60) | OPRM1CHRM2CHRM3CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL1814858 | 0.81 | OPRM1 (0.62) | OPRM1CHRM2CHRM3CCR5SIGMAR1 | |
| SCHEMBL4193616 | 0.80 | OPRM1 (0.70) | OPRM1CHRM2CHRM3CCR5KCNH2 | |
| SCHEMBL4197879 | 0.80 | OPRM1 (0.53) | OPRM1CHRM2CHRM3CCR5PKM | |
| SCHEMBL13853360 | 0.80 | OPRM1 (0.53) | OPRM1CHRM2CHRM3CCR5PKM | |
| SCHEMBL1220330 | 0.79 | OPRM1 (0.59) | OPRM1CHRM2CHRM3KCNH2SIGMAR1 | |
| SCHEMBL27815666 | 0.79 | CHRM2 (0.56) | OPRM1CHRM2CHRM3PKMSIGMAR1 | |
| SCHEMBL3817982 | 0.79 | OPRM1 (0.59) | OPRM1CHRM2CHRM3KCNH2SIGMAR1 | |
| SCHEMBL14276915 | 0.78 | OPRM1 (0.58) | OPRM1CHRM2CHRM3CCR5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| WO-2007116313-A2 | PYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE CCR5 RECEPTORS | PFIZER LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CX3CR1 | OPRM1 29/4885CHRM2 269/4885CHRM3 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.