SCHEMBL4125045

SCHEMBL4125045

CCCCc1ccc([C](C)Cc2ccc(C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
RARB P10826 2/20 0.47
PLK1 P53350 1/20 0.47
THRA P10827 2/20 0.46
THRB P10828 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14664345 0.81 NPC1 (0.63) ALDH1A1HPGDHSD17B10RARBPLK1
P-Xylene SCHEMBL9064447 0.81 CA2 (0.56) ALDH1A1HPGDHSD17B10RARBPLK1
SCHEMBL168272 0.81 CA2 (0.56) ALDH1A1HPGDHSD17B10RARBPLK1
SCHEMBL365821 0.79 CA2 (0.54) ALDH1A1HPGDHSD17B10RARBPLK1
Ammonia Solution, Strong SCHEMBL9428103 0.79 CA2 (0.54) ALDH1A1HPGDHSD17B10RARBPLK1
Acetic Acid SCHEMBL8583603 0.78 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10RARBPLK1
SCHEMBL12620502 0.76 HAO1 (0.60) ALDH1A1HPGDHSD17B10RARBPLK1
SCHEMBL6986997 0.76 KMT2A (0.51) ALDH1A1HPGDLMNA
SCHEMBL2299272 0.76 L3MBTL1 (0.49) LMNA
SCHEMBL2536910 0.76 THRA (0.59) ALDH1A1HPGDHSD17B10RARBPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090170705-A1 PHYLLOSILICATE FORMULATIONS FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES BAYER TECHNOLOGY SERVICES GMBH (DE) 2009-07-02 US disclosed