SCHEMBL412539

SCHEMBL412539

CCCCCCCCCCCCOC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.54
LGALS3 P17931 3/20 0.54
LGALS4 P56470 3/20 0.54
GJB2 P29033 5/20 0.51
ENGASE Q8NFI3 1/20 0.44
TLR4 O00206 1/20 0.43
AMY2A P04746 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804026 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4GJB2ENGASE
SCHEMBL4990033 0.95 LGALS8 (0.50) LGALS8LGALS3LGALS4GJB2ENGASE
SCHEMBL8439367 0.95 LGALS8 (0.50) LGALS8LGALS3LGALS4GJB2ENGASE
SCHEMBL17688998 0.93 LGALS8 (0.52) LGALS8LGALS3LGALS4GJB2AMY2A
SCHEMBL17688996 0.91 GJB2 (0.50) LGALS8LGALS3LGALS4GJB2ENGASE
SCHEMBL15295476 0.88 LGALS8 (0.54) LGALS8LGALS3LGALS4GJB2ENGASE
SCHEMBL8491597 0.88 LGALS3 (0.52) LGALS8LGALS3LGALS4ENGASEAMY2A
SCHEMBL18199629 0.87 TLR4 (0.51) LGALS8LGALS3LGALS4GJB2TLR4
SCHEMBL10016614 0.87 TLR4 (0.51) LGALS8LGALS3LGALS4GJB2TLR4
SCHEMBL9999695 0.87 TLR4 (0.51) LGALS8LGALS3LGALS4GJB2TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041775-A1 COMPOSITIONS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC (US) 2026-02-12 US disclosed
US-11173209-B2 Compositions for drug administration AEGIS THERAPEUTICS, LLC (US) 2021-11-16 US disclosed
US-20210121573-A1 ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC 2021-04-29 US disclosed
US-20200138956-A1 COMPOSITIONS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC 2020-05-07 US disclosed
US-10576156-B2 Compositions for drug administration AEGIS THERAPEUTICS, LLC (US) 2020-03-03 US disclosed
US-20190209689-A1 ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS LLC (US) 2019-07-11 US disclosed
US-10265402-B2 Absorption enhancers for drug administration AEGIS THERAPEUTICS, LLC (US) 2019-04-23 US disclosed
US-20180325994-A1 ANTI-BACTERIAL COMPOSITIONS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC 2018-11-15 US disclosed
US-20180221489-A1 ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC 2018-08-09 US disclosed
US-20180169247-A1 COMPOSITIONS FOR DRUG ADMINISTRATION AEGIS THERAPEUTICS, LLC 2018-06-21 US disclosed
WO-2006025882-A2 ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION THE UAB RESEARCH FOUNDATION (US) 2006-03-09 WO disclosed
US-20060046962-A1 Absorption enhancers for drug administration AEGIS THERAPEUTICS LLC (US) 2006-03-02 US disclosed
US-20060045868-A1 Absorption enhancers for drug administration AEGIS THERAPEUTICS LLC 2006-03-02 US disclosed
US-20060046969-A1 Antibacterial compositions for drug administration AEGIS THERAPEUTICS LLC (US) 2006-03-02 US disclosed
US-20060045869-A1 Absorption enhancers for drug administration AEGIS THERAPEUTICS LLC 2006-03-02 US disclosed
EP-0254771-B2 Detection of microbes in a sample EDBERG STEPHEN C (US) 2000-02-02 EP disclosed
US-5661130-A NONTOXIC, NONIONIC ALKYL GLYCOSIDE HAVING A HYDROPHOBIC ALKYL JOINED BY A LINKAGE TO A HYDROPHILIC SACCHARIDE THE UAB RESEARCH FOUNDATION (US) 1997-08-26 US disclosed
WO-1995000151-A1 ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION UAB RESEARCH FOUNDATION (US) 1995-01-05 WO disclosed
US-4925789-A COLORIMETRIC ANALYSIS EDBERG STEPHEN C (US) 1990-05-15 US disclosed
EP-0254771-A2 Detection of microbes in a sample Edberg, Stephen C. (US) 1988-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11173209-B2 Compositions for drug administration SLC10A1, ABCB11, CSGALNACT1 LGALS8 34/4885LGALS3 28/4885LGALS4 47/4885
US-20180169247-A1 COMPOSITIONS FOR DRUG ADMINISTRATION SLC10A1, ABCB11, CSGALNACT1 LGALS8 34/4885LGALS3 28/4885LGALS4 47/4885
US-20260041775-A1 COMPOSITIONS FOR DRUG ADMINISTRATION SLC2A8, SLC5A2, SLC2A4 LGALS8 724/4885LGALS3 1331/4885LGALS4 752/4885
US-20200138956-A1 COMPOSITIONS FOR DRUG ADMINISTRATION SLC10A1, ABCB11, CSGALNACT1 LGALS8 34/4885LGALS3 28/4885LGALS4 47/4885
US-10576156-B2 Compositions for drug administration SLC10A1, ABCB11, CSGALNACT1 LGALS8 34/4885LGALS3 28/4885LGALS4 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.