Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.64 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736702 | 0.91 | ALOX15 (0.71) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL16117670 | 0.88 | ALDH1A1 (0.67) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL24945817 | 0.87 | ALDH1A1 (0.54) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9503098 | 0.86 | ALDH1A1 (0.71) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10938794 | 0.86 | TSHR (0.52) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL16117675 | 0.82 | ALDH1A1 (0.58) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL23959962 | 0.82 | ALDH1A1 (0.46) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL67854 | 0.82 | ALOX15 (0.82) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL13911912 | 0.82 | ALDH1A1 (0.41) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10907968 | 0.81 | ALDH1A1 (0.56) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016190871-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. (US) | 2016-12-01 | — | — | WO | disclosed |
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| EP-1890993-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR ANTAGONISTS OF GLYR | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006121390-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR AGONISTS OF GLYR | ASTRAZENECA AB (SE) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | GLRA1, GLRB, GPBAR1 | ALOX15 1015/4885ALDH1A1 1413/4885SMN1; SMN2 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.