Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl N-Methylcarbamate SCHEMBL4139606 | 0.98 | EPHX1 (0.50) | EPHX1ALDH1A1TOP2ATOP2BCA12 | |
| Benzyl N-Methylcarbamate SCHEMBL645204 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL6510776 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL6461910 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL6444513 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL28652926 | 0.83 | MEN1 (0.56) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL5586442 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL5156651 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| Benzyl N-Methylcarbamate SCHEMBL11110653 | 0.81 | CTSS (0.53) | ALDH1A1TOP2ATOP2BCA12CA1 | |
| SCHEMBL3107991 | 0.79 | LMNA (0.58) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | HTR2C, HTR2A, HTR5A | EPHX1 892/4885ALDH1A1 1292/4885TOP2A 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.