Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 5/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071418 | 0.96 | FBP1 (0.41) | FBP1RNASELP2RY14 | |
| SCHEMBL12920258 | 0.91 | FBP1 (0.47) | FBP1RNASELP2RY14 | |
| SCHEMBL13297099 | 0.91 | FBP1 (0.47) | FBP1RNASELP2RY14 | |
| SCHEMBL18674199 | 0.91 | FBP1 (0.47) | FBP1RNASELP2RY14 | |
| SCHEMBL16939202 | 0.91 | FBP1 (0.47) | FBP1RNASELP2RY14 | |
| SCHEMBL10188789 | 0.90 | FBP1 (0.49) | FBP1RNASELP2RY14 | |
| SCHEMBL12600819 | 0.89 | FBP1 (0.50) | FBP1RNASEL | |
| SCHEMBL12600856 | 0.89 | FBP1 (0.50) | FBP1RNASEL | |
| SCHEMBL14925705 | 0.86 | FBP1 (0.39) | FBP1RNASEL | |
| SCHEMBL16943260 | 0.86 | FBP1 (0.39) | FBP1RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884885-B2 | Synthesis of labile base protected-modified deoxy and modified ribo nucleosides, corresponding phosphoramidites and supports and their use in high purity oligonucleotide synthesis | CHEMGENES CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |
| US-8933214-B2 | RNA synthesis—phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end | CHEMGENES CORPORATION (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130072670-A1 | RNA SYNTHESIS-PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION, AND APPLICATION IN CONVENIENT INTRODUCTION OF LIGANDS, CHROMOPHORES AND MODIFICATIONS OF SYNTHETIC RNA AT THE 3'-END | CHEMGENES CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-8309707-B2 | RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end | CHEMGENES CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120065386-A1 | SYNTHESIS OF LABILE BASE PROTECTED - MODIFIED DEOXY & MODIFIED RIBO NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND SUPPORTS AND THEIR USE IN HIGH PURITY OLIGONUCLEOTIDE SYNTHESIS | CHEMGENES CORPORATION | 2012-03-15 | — | — | US | disclosed |
| US-20100324278-A1 | RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3'-end | CHEMGENES CORPORATION | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065386-A1 | SYNTHESIS OF LABILE BASE PROTECTED - MODIFIED DEOXY & MODIFIED RIBO NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND SUPPORTS AND THEIR USE IN HIGH PURITY OLIGONUCLEOTIDE SYNTHESIS | RNMT, POLRMT, RNGTT | FBP1 2040/4885RNASEL 55/4885P2RY14 1850/4885 |
| US-20100324278-A1 | RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3'-end | NSUN3, RNMT, NSUN2 | FBP1 2482/4885RNASEL 108/4885P2RY14 1502/4885 |
| US-20130072670-A1 | RNA SYNTHESIS-PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION, AND APPLICATION IN CONVENIENT INTRODUCTION OF LIGANDS, CHROMOPHORES AND MODIFICATIONS OF SYNTHETIC RNA AT THE 3'-END | NSUN3, RNMT, NSUN2 | FBP1 2482/4885RNASEL 108/4885P2RY14 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.