SCHEMBL412806

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13390017	0.97	LMNA (0.45)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL10189695	0.93	LMNA (0.45)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL10189838	0.88	LMNA (0.43)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL408635	0.86	LMNA (0.45)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL3306339	0.85	LMNA (0.50)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL408751	0.85	LMNA (0.50)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL3302673	0.83	ALDH1A1 (0.48)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	Hydrochloric Acid SCHEMBL407548	0.83	ALDH1A1 (0.47)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL10189689	0.83	NPSR1 (0.49)	LMNANPSR1CYP1A2CYP3A4CYP2D6
	SCHEMBL3302459	0.82	ALDH1A1 (0.47)	LMNANPSR1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.