Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999626 | 0.84 | TSHR (0.42) | THRBTSHRALDH1A1CYP3A4AKR1B10 | |
| SCHEMBL9852431 | 0.84 | TSHR (0.43) | TSHRALDH1A1CYP3A4TP53HSD17B10 | |
| SCHEMBL27694521 | 0.82 | CYP3A4 (0.39) | TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9487209 | 0.81 | TSHR (0.40) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL27812824 | 0.81 | TSHR (0.40) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL9487489 | 0.81 | TSHR (0.40) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL17893001 | 0.79 | TSHR (0.39) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL27812818 | 0.79 | CYP3A4 (0.36) | THRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL3623072 | 0.78 | OPRM1 (0.40) | TSHRALDH1A1HPGD | |
| SCHEMBL27999808 | 0.77 | ALDH1A1 (0.35) | ALDH1A1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090079913-A1 | Optically anisotropic film, polarizing film, producing process thereof, and application use thereof | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |