Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134212 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAMAPTNPC1 | |
| SCHEMBL4113737 | 0.86 | TAS1R3 (0.39) | ALDH1A1LMNAKDM4EHPGDGAA | |
| SCHEMBL4123787 | 0.83 | MAPT (0.41) | ALDH1A1LMNAKDM4EGAAMAPT | |
| SCHEMBL4117083 | 0.81 | PTGS1 (0.39) | ALDH1A1LMNAKDM4EHPGDMAPT | |
| SCHEMBL4125922 | 0.80 | PTPN1 (0.43) | TDP1KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL4134426 | 0.79 | ALDH1A1 (0.46) | TDP1ALDH1A1LMNAHPGDGAA | |
| SCHEMBL4121697 | 0.79 | MAPT (0.44) | ALDH1A1MAPTPOLBRAB9AMEN1 | |
| SCHEMBL4115886 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1LMNAKDM4EGAATNFRSF1A | |
| SCHEMBL4122587 | 0.77 | ADRA2A (0.36) | TDP1ALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL4135380 | 0.74 | NPC1 (0.49) | ALDH1A1LMNAHPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | GLRA1, GLRB, GPBAR1 | TDP1 3398/4885ALDH1A1 1413/4885LMNA 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.